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Transmissible spongiform encephalopathy agents: safe working and the prevention of infection
Guidance from the Advisory Committee on Dangerous Pathogens and the Spongiform Encephalopathy Advisory Committee

This revised guidance was published in June 2003 onwards in sections, as they were prepared and endorsed by ACDP, SEAC and the Joint Working Group.

Publishing in this way facilitates easier updating of individual sections by the ACDP TSE Working Group as further scientific information becomes available or future policy decisions need to be reflected.

The date of publication for updated or revised sections is clearly indicated. This guidance replaces the edition issued in March 1998.

Foreword
Statement on ACDP/SEAC
Abbreviations
   
Part 1
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Introduction pdf (40kb)
Part 2
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Health and Safety management of TSEs pdf(35kb)
Part 3
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Laboratory containment and control measures pdf(155kb)
Part 4
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Infection control of CJD and related disorders in the healthcare setting (revised July 2005) pdf(62kb) - updated 30 Mar 2007 - corrected 14 May 2007
Annex A.1
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Distribution of TSE Infectivity in human tissues and body fluids pdf(40kb) - updated 1 May 2008
Annex A.2
 Distribution of infectivity in animal tissue and body fluids pdf(68kb) - updated 7 February 2007
Annex B
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Diagnostic criteria pdf(19kb)
Annex C
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Decontamination and waste disposal pdf(152kb)
Annex D
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Transport of TSE-infected material pdf(96kb) - 6 December 2007: this Annex is now out of date. The ACDP TSE Working Group is currently drafting a new Annex, which will be published as soon as possible.
Annex E
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Quarantining of surgical instruments pdf(16kb) - amended 29 January 2008
Annex F
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Endoscopy pdf(225kb) - revised and updated 02 June 2008
Endoscopy and individuals at risk of vCJD for public health purposes pdf (54kb)- revised and updated 02 June 2008: A consensus statement from the BSG Decontamination Working Group and the ACDP TSE Working Group
Annex G
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Decontamination of other specialised equipment - This Annex is currently being revised and will be available soon
Annex H
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After death pdf(25kb)
Information sheet for funeral directors, relatives and others following a CJD death pdf (18 kb) - published May 2007
Annex I
-Outline protocol for management of instruments and tissues from brain biopsy procedures on patients with progressive neurological disorders pdf(48kb) -
amended May 2007
Annex J
-Assessment to be carried out before surgery and endoscopy to identify patients with, or at risk of, CJD pdf updated 1 May 2008 (64kb)
  
Acknowledgements
  
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