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The template is designed to show the breadth of expertise available to the Committee and is intended to aid members in discussing future needs with regard to expertise necessary to fulfil the terms of reference of the COM. The compliment of COM is 13 members (9 specialists and 3 lay members) and one chair. A deputy chair has not been appointed.

	Chair: Leadership, presentation of questions/referrals to members. representation of COM views to media. Expertise in mutagenicity evaluation.						1.Questions for committee Referrals. 2. Advice to CMO/Chair Food Standards, Government Departments; Publication of advice on Internet site
Input from COC/COT on.Carcinogenicity/ Toxicity of chemicals.			Committee evaluation of specialist advice. Overall advice on risk of Mutagenicity
Structure Activity Relationships Mutagenicity test strategies Mutagenicity test strategies Mutagenicity test strategies			Metabolism and activation of chemicals to promutagens. Evaluation of DNA/protein adducts.		In-vitro testing. Mutageneicity; Gene, Chromosomal Aneuploidy Bacteria or Mammalian cell methods Evaluation of aneuploidy			In-vivo testing: Assessment of current bone marrow methods and rat liver UDS assays Risk assessment of mutagens
Development of new test methods. Assessment of new methods, e.g Use of transgenic animal models. Development of novel method for measuring interaction with DNA(such as AMS). Molecular biology of mutagenesis.							Provision of lay overview of scientific advice, and input to drafting of documents.

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