Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (non-food) - COT

What's new

20 September 2007

Statement on BALPA is now available.

The relevant discussion papers are also available below:

TOX/07/20 - UPDATE DISCUSSION PAPER ON THE REVIEW OF THE CABIN AIR ENVIRONMENT, ILL-HEALTH IN AIRCRAFT CREWS AND THE POSSIBLE RELATIONSHIP TO SMOKE/FUME EVENTS IN AIRCRAFT

(Previous discussion papers TOX/06/21, TOX/06/39 and TOX/07/10)

Annex 1: Extract of Minutes of COT meeting held 20 March 2007. Update discussion paper on the cabin air environment, ill-health in aircraft crews and the possible relationship to smoke/fume events in aircraft TOX/2007/10.

Annex 2: Further consideration of approaches to evaluation of sensory irritation in cabin air. Submission of data from Professor P Wolkoff (National Research Centre for Working Environment, Denmark).

Annex 3: Commentary on further consideration of neuropsychological effects reported in pilots - exposure to carbon monoxide in TOX/2007/10. Professor M Bagshaw, King's College London and Cranfield University.

Annex 4: Engine bleed air and aircraft air quality testing for BAe 146-200 aircraft registration number SE-DRE.

Annex 5: Further review of epidemiological data. Overview of case reports, health-related incident reports and testimonies. Table 1; Table 2 and Table 3.

Annex 6: Minutes of meeting held to discuss research aspects of COT review of BALPA submission on cabin air quality, 2 May 2007.

Annex 7: Draft working paper.

 

TOX/07/10 - UPDATE DISCUSSION PAPER (MARCH 2007) ON THE REVIEW OF THE CABIN AIR ENVIRONMENT, ILL-HEALTH IN AIRCRAFT CREWS AND THE POSSIBLE RELATIONSHIP TO SMOKE/FUME EVENTS IN AIRCRAFT

(Previous discussion papers TOX/06/21 and TOX/06/39)

Annex 1 : Extract from minutes of COT meeting held 5 December 2006.

Annex 2.1 : Further consideration of sensory irritant potential of air contaminants potentially present in commercial aircraft, plus selected paper Nielsen GD, Wolkoff P and Alarie Y (2007). Sensory irritation: risk assessment approaches. Regulatory Toxicology and Pharmacology, advance publication in e-format.

Annex 2.2 : Selected papers on prediction of sensory irritation.

Annex 3 : Minutes of meeting held between Dr M Abraham (University College, London) and HPA COT Secretariat, 20 February 2007.

Annex 4 : Further consideration of neuropsychological effects reported in pilots - exposure to carbon monoxide.

Annex 5.1 : Pilot skill tests and proficiency checks.

Annex 5.2 : Civil Aviation Authority Standards Document 24, Version 05. Guidance to examiners: multi-pilot aeroplanes (MPA) type rating skill tests and proficiency checks.

Annex 5.3 : Civil Aviation Authority document CAP 737. Crew resource management (CRM) training. Guidance for flight crew CRM instructors (CRMIS) and CRM Instructor-Examiners (CRMIES). (Chapters 1, 2, 4 and 7 selected.)

Annex 5.4: Civil Aviation Authority forms: 1) LST/LPC MPA Issue 2 (SRG\1158). MPA (multi-pilot aeroplanes) type rating, skill test and proficiency check schedule - examiner's record and guidance, 2) LST/LPC SPA/MPA Issue 9 (SRG\1119). Type/instrument/class ratings (aeroplane), licensing/ATPL skill test and proficiency check - application and guidance.

Annex 6: In-confidence for Members only. British Airways pilot training, checking and grading.

Annex 7: In-confidence for Members only. FlyBe pilot checking and grading.

Annex 8: Ryan JJ and Schnakenberg-Ott SD (2003). Scoring Reliability on the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III). Assessment 10(2):151-159.

Annex 9 : Commentary on the applicability of pilot test/check data for neuropsychological assessment purposes. Professor R Morris, Professor of Neuropsychology at the Institute of Psychiatry, Kings College Hospital, London.

Annex 10 : Further evaluation of epidemiological data. Table 1 Table 2 Table 3 Table 4 T4 foot notes Tables 5-6 addT 5-6 cases T5-6 acronyms

Annex 11 : Selected epidemiological papers.

Annex 12 : HPA COT Secretariat visit to a BA B767 flight simulator

TOX/06/39 - UPDATE DISCUSSION PAPER (DECEMBER 2006) ON THE CABIN AIR ENVIRONMENT, ILL-HEALTH IN AIRCRAFT CREWS AND THE POSSIBLE RELATIONSHIP TO SMOKE/FUME EVENTS IN AIRCRAFT

Annex 1 : Extract from minutes of COT meeting held 11 July 2006.

Annex 2 : Minutes of meeting held between BALPA and HPA COT secretariat, 25 July 2006.

Annex 3 : Minutes of meeting held between BATA and HPA COT secretariat, 3 August 2006.

Annex 4 : Minutes of meeting held between CAA and HPA COT secretariat, 3 August 2006.

Annex 5 : Minutes of meeting held between BRE and HPA COT secretariat, 21 September 2006.

Annex 6 : Minutes of meeting held between Dr D O'Hare (Imperial College) and HPA COT secretariat, 25 September 2006.

Annex 7 : Minutes of meeting held between FlyBe and HPA COT secretariat, 2 October 2006.

Annex 8 : Minutes of meeting held between BA and HPA COT secretariat, 9 October 2006.

Annex 9 : Formulation details of jet oils and MSDS data.

Annex 10: For members use only. Presentation by Shell Global Solutions 1999.

Annex 11 : Thermal decomposition of oils submitted by Honeywell Aerospace.

Annex 12a: For members use only. Society of Automotive Engineers report on pyrolysis of two jet oils and exposure determination in cabin air.

Annex 12b : Summary of published test-rig study using Garrett turboprop engine.

Annex 12c : Overview of published exposure data.

Annex 13 : Information submitted by FlyBe on incident monitoring.

Annex 14 : Information submitted by British Airways on incident monitoring.

Annex 15 : Development of an approach to exposure monitoring.

Annex 16 : Commentary on neuropsychology data submitted to COT. Professor R Morris, Professor of Neuropsychology at the Institute of Psychiatry, Kings College Hospital, London.

Annex 17: In-confidence for members use only. Review of analyses undertaken by Biolab Medical Unit on pilots.

Annex 18 : Meeting between DHL AIR LTD and the HPA COT Secretariat

TOX/06/21 - Discussion paper on the cabin air environment, ill health in aircraft crews and the possible relationship to smoke/fume events in aircraft

Annex 1A , addendum and Annex 1B - Summary of BALPA submission Annex 1C - Additional papers identified by secretariat

Annex 2 - Summary of BALPA conference held at Imperial College, London April 2005

Annex 3 - Meeting with BALPA
Evaluation of BALPA Master Fume Database

Annex 4 - Meeting with CAA
Evalaution of CAA MOR database MOR pyramid

Annex 5 - Meeting with BAe, Boeing, Rolls Royce and Honeywell additional data from RR air conditioning BAe 146 B757 Engine addendum

Annex 6 - Initial information submitted by British Airways

Annex 7 - Secretariat summary of Neuropsychology evaluation of pilots (In confidence for members only)

Annex 8 - Preliminary information on TCP in filters from B757 (In confidence for members only)

Annex 9 - Summary data on potential exposures in aircraft

Annex 10 - Information provided by the Building Research Centre on the development of a capture device for aircraft contaminant exposure monitoring, and information on the ideal Cabin Environment (ICE) research project

Annex 11- Mackerer CR et al J Toxicology Environmental health, part A, 56, 293-328, 1999

Annex 12 - Data on blood tests from pilots (In confidence for members only)

Contact address

Mr Khandu Mistry
Room 523
Department of Health
Wellington House
133 - 155 Waterloo Road
London SE1 8UG

Tel: +44 (0)20 7972 4946
Fax: +44 (0)20 7972 1001
Email: Khandu.Mistry@dh.gsi.gov.uk

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Since 1st April 2000, food issues have become the responsibility of the Food Standards Agency.

• For Committee work related to food items please visit: www.food.gov.uk/science/ouradvisors/toxicity/
• To access Committee archive material please visit:
  http://archive.food.gov.uk/dept_health/archive/cot.htm

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